Sakae Naa has effects that are similar to M. speciosa. In Asia it’s favoured for the energizing, stimulating feeling which some users experience as a ‘rush’ not unlike the rush one feels from caffeine. Secondary effects included mood-lifting and mild sedative effects. For the sole intent of relaxation Sakae Naa is not the best option available, but in combination with work or other activities it provides a pleasant stimulus. Effects come on quickly and last up to 4 hours.
Do not to participate in traffic or other activities that demand your concentration. Usage of Combretum quadrangulare in high dosages may be mildly addictive. Acute side effects include dry mouth, loss of appetite and constipation. Side effects from long term use include anorexia and weight loss, insomnia, and a darkening of the skin, particularly on the cheeks. Do not combine with MAO-inhibitors. Keep out of reach of children.